Example:

You'll find a picture of that bad boy on all the letterheads and stuff. Why of course, it is the church. What respectful Catholic university wouldn't have it's church as it's iconic building!? Oh wait... shit. Zingerrrr. In their defense though, imagine the shit-storm that would arise over covering the roof of the entire church in gold. Good times, I'm sure.
What other buildings are there? I'm sure OSU has one, but I really don't know what it is. Miami? UC? Your school/alma mater?
For P-town, I propose the bridges over Sharon Rd. Unorthodox, sure. But maybe that's why...